Can CBH Manage Hosts in Regions or VPCs Different from that of the CBH Instance?

Yes.

CBH can only directly manage resources in the same VPC as that of the CBH instance.

Although you can establish cross-region or cross-VPC network connections between a CBH instance and resources, such connections may be not stable enough for using the CBH system. If you really need to use CBH for cross-VPC or cross-region resource management, you can:

• Use a VPC peering connection to connect two VPCs.
• Use a Cloud Connect (CC), Virtual Private Network (VPN), or the like, to establish a cross-region network connection.
• Direct Connect does not support dual-stack networks, and virtual IP addresses cannot be connected.